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Understanding Heart Disease Risk - Comparing Risk Scores with Calcium Scans in Healthy Adults of Coastal Karnataka

A Study of Association between Framingham Risk Score (FRS), ASCVD (Atherosclerotic Cardiovascular Disease) risk score and QRISK3 Score with CT Coronary Artery Calcium Score (CAC) in Asymptomatic individuals of Coastal Karnataka - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/097133
Enrollment
140
Registered
2025-11-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E66- Overweight and obesity Health Condition 2: Z68- Body mass index [BMI] Health Condition 3: E08-E13- Diabetes mellitus Health Condition 4: I10- Essential (primary) hypertension Health Condition 5: I15- Secondary hypertension Health Condition 6: I700- Atherosclerosis of aorta Health Condition 7: I73- Other peripheral vascular diseases Health Condition 8: E78- Disorders of lipoprotein metabolism and other lipidemias

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Department of General Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Asymptomatic people with pre-diagnosed/undiagnosed risk factors for CVD Asymptomatic people without any risk factors for CVD Who are above 30 years of age with or without ECG changes, ECHO changes, without typical ACS symptoms or anginal symptoms who are willing to undergo Coronary CT calcium scan for CAC scoring and visit KH.

Exclusion criteria

Exclusion criteria: Coronary artery disease CAD with Coronary-artery bypass grafting RHD CHD Cardiac arrhythmias Malignancy-Lymphoma, Multiple myeloma, bronchogenic carcinoma, Carcinoma breast etc CKD Thyroid and Parathyroid disorders – Hyperparathyroidism, Hypothyroidism, Primary Parathyroidsm Hypervitaminosis D Critically ill patients Morbidly Obese Pregnancy Symptoms of active Coronary disease Stroke

Design outcomes

Primary

MeasureTime frame
•To look for the correlation between the three calculated risk scores (FRS, ASCVD, QRISK3) and the CAC Score in the Study PopulationTimepoint: Cross sectional study, No followup, All data about history, comorbidities, CT scan data, CAG reports if any are collected at same time within the data colection period of the trial (15/11/25 to 31/3/27)

Secondary

MeasureTime frame
Identify discrepancies between risk scores & the actual burden of subclinical atherosclerosis as measured by CAC SCORE.Timepoint: At baseline;Determine which risk score (FRS, ASCVD, or QRISK3) best correlates with CAC SCORE in our populationTimepoint: At baseline;Explore clinical factors that may influence the correlation between risk scores & CAC ScoreTimepoint: At baseline;To compare the risk scores & CAC discrepancies in diabetics & non-diabeticsTimepoint: At baseline;To assess the correlation between number of vessel involvements in CAC CT scan & the major risk factors of CVDTimepoint: At baseline;To assess the correlation between the various risk scores & Coronary Angiography proven atherosclerotic individualsTimepoint: At baseline

Countries

India

Contacts

Public ContactDr Shivashankara K N

Kasturba Hospital, Manipal

shi.sha@manipal.edu9448623861

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026