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Comparison of Dexmedetomidine given via nasal route and oral pregabalin for stress and pain control in Lumbar spine surgery

A comparative evaluative study between the effects of preoperative intranasal dexmedetomidine and oral pregabalin in patient undergoing lumbar spine fixation surgery - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097117
Enrollment
96
Registered
2025-11-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S320- Fracture of lumbar vertebra

Interventions

Intervention1: Intranasal Dexmedetomidine: One group will receive Intranasal Dexmedetomidine at a dose of 2 mcg/kg 45 minutes before operation Intervention2: Nil: Nil Control Intervention1: Oral Prega

Sponsors

R.G.Kar Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing Lumbar spine fixation surgery ASA I or II patients Patients who give written informed consent

Exclusion criteria

Exclusion criteria: Patients who refuse to give written informed consent Patients who are allergic to any of the drugs used in the study Chronic alcoholism Neurological or cardiac disease

Design outcomes

Primary

MeasureTime frame
. To compare duration of postoperative analgesia and total amount of analgesic requirementTimepoint: in first 24 hours after operation

Secondary

MeasureTime frame
e intra operative and post operative haemodynamic parameters any differences in recovery time from anaesthesia any differences in Patient’s satisfaction score any postoperative adverse effect Timepoint: in first 24 hours after operation

Countries

India

Contacts

Public ContactSaikat Niyogi

R.G.Kar Medical College and Hospital

saikatneuro1972@gmail.com9831732443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026