Health Condition 1: F329- Major depressive disorder, singleepisode, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Vardhman Mahavir Medical College Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Moderate to severe depressive disorder as per ICD 11 Diagnostic Criteria (MADRS greater than or equal to 20) Treatment naive or not taking any antidepressant therapy since the last 4 weeks Individuals who can read and write in either Hindi or English language
Exclusion criteria
Exclusion criteria: Patients with any other neuropsychiatric disorders such as schizophrenia epilepsy dementia and bipolar disorder Organic diseases leading to depression Other serious underlying diseases organ dysfunction and malignant tumor comorbidities History of brain surgery and injury Patients with High Suicidal Risk based on clinical assessment Contraindications to medication and treatment methods in this study such as ferromagnetic implants in the head a history of neurosurgical operations or a pacemaker implant medication that lower the threshold of epileptic seizures (eg Clozapine Pethidine Aminophylline)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in depressive symptom severity as measured by the Montgomery Asberg Depression Rating Scale (MADRS)Timepoint: Baseline At 4 weeks and at 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in cognitive function, as measured by the Montreal Cognitive Assessment (MoCA) + Trail Making Test (TMT) + Stroop TestTimepoint: Baseline measurement before giving rTMS and follow up measurement at 2 weeks and 4 weeks after giving rTMS. | — |
Countries
India
Contacts
Public ContactSHIVRAM
Vardhman Mahavir Medical College and Safdarjung Hospital New Delhi India 110029
Outcome results
None listed