Health Condition 1: O- Medical and Surgical Health Condition 2: C00-D49- Neoplasms
Conditions
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consenting patients more than 18 years of age, undergoing elective major abdominal surgeries including Liver, pancreatic, cytoreductive surgery with or without HIPEC. 2. Patients undergoing open, laparoscopic, laparoscopic-assisted, laparoscopic converted and robotic procedures.
Exclusion criteria
Exclusion criteria: 1. Patients not willing to consent 2. Patients undergoing surgical procedures other than those mentioned above 3. Patients undergoing planned or unplanned nephrectomy 4. Patients with pre-existing renal disease (previous history of AKI according to KDIGO criteria) 5. Post kidney transplant patient 6. Patients with end stage kidney disease on dialysis. 7. Renal replacement therapy (any form of dialysis) within the 90 days preceding the operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PO-AKI (an acute alteration in kidney function) within 7 days in patients undergoing major abdominal surgery including, Hepatic resection, Pancreatic surgery, cytoreductive surgery with or without HIPECTimepoint: Within first 7 days after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of Early PO-AKI ( AKI occurring within 48 hrs after surgery) 2. Incidence of AKD (a sustained alteration in kidney function over a 3-month period i.e. persisting after 7 days until 3 months after surgery) 3. Incidence of CKD (a sustained alteration in kidney function persisting beyond 3 months) 4. Long term impact of PO-AKI on kidney function at first follow up visit within 3 month after discharge, 6 months and 1 year with serum creatinine value 5. Identify factors associated with PO-AKI. 6. Association between PO-AKI and postoperative length of stay 7. Need for CRRT/ dialysis during hospital stay and until one year 8. Need for reduction/omission of chemotherapeutic drugs in postoperative chemotherapy due impaired renal function. Timepoint: at 48 hours, at the time of discharge (within 72 hours of discharge) and at 3, 6, 12 months | — |
Countries
India
Contacts
Public ContactDr Gajanan Vaidya
Tata Memorial Hospital
Outcome results
None listed