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Study on how different breathing methods affect lung health in patients having video-assisted surgery for esophageal cancer

Comparison of Volume-Controlled Ventilation (VCV) and Pressure-Controlled Ventilation with Volume Guarantee (PCV-VG) on Respiratory Mechanics During Video-Assisted Thoracoscopic Surgery-Esophagectomy: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097096
Enrollment
70
Registered
2025-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: pressure control with volume guarantee mode of ventilation: During anaesthesia in esophagus surgery, the patient will be ventilated using the pressure control-volume guarantee mode of v

Sponsors

North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: age of more than 18 years sex both males and females American Society of Anesthesiologists physical status o 1 to 3 Body mass index of less than 30 Adequate baseline pulmonary function

Exclusion criteria

Exclusion criteria: Any emergency surgery American Society of Anesthesiologists physical status 4 or above severe chronic obstructive and restrictive pulmonary disease Severe renal or cardiac and hepatic dysfunction Pregnancy Active respiratory infection Previous thoracic surgery on operating side

Design outcomes

Primary

MeasureTime frame
Peak inspiratory pressure (PIP), Dynamic compliance (Cdyn), Mean airway pressure (Pmean) and Plateau pressure (Pplat)Timepoint: baseline at just after induction of anaesthesia 15 min after pneumothorax creation 30 min after pneumothorax creation 45 min after pneumothorax creation 60 min after pneumothorax creation 75 min after pneumothorax creation 90 min after pneumothorax creation 105 min after pneumothorax creation 120 min after pneumothorax creation 15 minutes after completion of VATS surgery—

Secondary

MeasureTime frame
ABG parameter including pH, PO2, PCO2, & PO2/FiO2 ratioTimepoint: baseline just after induction of anaesthesia 30 min after pneumothorax creation 15 minutes after completion of VATS surgery;Haemodynamic parameter (HR, MAP, SPO2), EtCO2, autoPEEP,Timepoint: Baseline at just after induction of anaesthesia 15 min after pneumothorax creation 30 min after pneumothorax creation 45 min after pneumothorax creation 60 min after pneumothorax creation 75 min after pneumothorax creation 90 min after pneumothorax creation 105 min after pneumothorax creation 120 min after pneumothorax creation 15 minutes after completion of VATS surgery;postoperative pulmonary complications (PPC)Timepoint: Baseline on Postoperative day 1 Postoperative day 2 Postoperative day 3 Postoperative day 4 Postoperative day 5 Postoperative day 6 Postoperative day 7—

Countries

India

Contacts

Public ContactSanju Sharma

North Eastern Indira Gandhi Regional Institute of Health & Medical Sciences

drsanjusharma84@gmail.com917461072669

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026