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A clinical study on the effect of vanapalandu in improving heart function in patients with weak ejection fraction

A clinical study on the effect of vanapalandu in kaphaja hridroga with special reference to low left ventricular ejection fraction A proof of concept study - nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097050
Enrollment
30
Registered
2025-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I501- Left ventricular failure, unspecified

Interventions

None listed

Sponsors

National Institute of Ayurveda Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients of both genders, with stable HF (NYHA classification up to Class III and reduced EF not more than 40% and not less than 15%. 2. Patients who have already taken conventional therapy for more than or equal to 3 months and yet have the above criteria would also be included.

Exclusion criteria

Exclusion criteria: 1.Patients with an Ejection Fraction of the Left Ventricle more than or equal to 40 percent and less than or equal to 15 percent will not be included in the study. 2.Patients with a history of Unstable Angina, Acute Myocardial infarction (newly diagnosed acute cases), valvular defects, congenital heart disease, pericarditis, arrhythmia, Pericardial effusion, uncontrolled Hypertension (more than or equal to 150/90 mm Hg) 3.Patients with a history of extra Cardiac ailments like renal failure, uncontrolled diabetes mellitus (HbA1c more than or equal to 8%) with or without complications, chronic alcoholics, and pregnant/lactating women.

Design outcomes

Primary

MeasureTime frame
Change present in ejection fraction in 2D echocardiography of the heart after 2 months of trial.Timepoint: 2 months

Secondary

MeasureTime frame
• Changes in signs and symptoms of Kaphaja Hridroga after 2 months of trial. • Changes in symptoms using a standardized tool, the KCC Questionnaire after 2 months of trial. • Frequency and severity of adverse effects documented during the intervention after 2 months of trial.Timepoint: 2 months

Countries

India

Contacts

Public ContactProf Udai Raj Saroj

National Institute of Ayurveda, Jaipur

ursarojayu@gmail.com9413063803

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026