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A study on how different sedation medicines affect recovery and outcomes in patients on ventilators in the Intensive Care Unit.

An observational study on the choice of sedation and clinical outcomes in mechanically ventilated patients in the Intensive Care Units of a tertiary care hospital - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/097048
Enrollment
323
Registered
2025-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: Nil: Nil

Sponsors

Shivakumar sindhur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients aged above 18 years 2 Patients who are mechanically ventilated with invasive ventilation within 48 hours of ICU admission 3 Patients who are receiving sedation and analgesia 4 Patient’s primary relatives are willing to consent to the study

Exclusion criteria

Exclusion criteria: 1 Patients diagnosed brain dead 2 Patients who are receiving palliative care 3 Patients admitted with head injury and neurological condition(stroke) 4 Patients who are on Mechanical ventilation for less than 48 hours post-surgery 5 Cardiac arrest (code blue) patient

Design outcomes

Primary

MeasureTime frame
Duration of Mechanical Ventilation, length of ICU and hospital stay, 28-day mortality, and ICU events (hypotension, delirium, ventilator-associated pneumonia, hospital-associated pressure injury, CLABSI, CAUTI, Bacteremia, dialysis).Timepoint: Duration of Mechanical Ventilation, length of ICU and hospital stay, 28-day mortality, and ICU events (hypotension, delirium, ventilator-associated pneumonia, hospital-associated pressure injury, CLABSI, CAUTI, Bacteremia, dialysis).

Secondary

MeasureTime frame
NILLTimepoint: NILL

Countries

India

Contacts

Public ContactDr Prima JJ DSouza

Manipal College of Nursing, Manipal

shivakumar.mconmpl2024@learner.manipal.edu6363681709

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026