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A Study Comparing how well a new Drug (Sugammadex) helps patients wake up from Muscle Relaxants when they’ve been given Magnesium sulphate before surgery

A clinical double-blind randomized controlled study comparing the efficacy of Sugammadex in reversing Vecuronium-induced neuromuscular blockade in patients pretreated with Magnesium Sulphate(MgSO4). - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/097036
Enrollment
150
Registered
2025-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Action of Magnesium Sulphate on neuromuscular blockade and reversal agent: Inj. Magensium Sulphate 40mg/kg in 100ml NS 30minutes before surgery Inj. Vecuronium 0.1mg/kg during the tim

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 and 2

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To compare and evaluate the efficacy of pre-treatment with Magnesium Sulphate vs Normal saline in Vecuronium-induced neuromuscular blockade (train-of four (TOF) more than 0.9) on the time of reversal with Sugammadex.Timepoint: The time taken to reach a train-of-four (TOF) ratio greater than 0.9 after administering Sugammadex.—

Secondary

MeasureTime frame
To evaluate the post-operative complication of both groupsTimepoint: 5 minutes post op 10 minutes post op 20 minutes post op 30 minutes post op—

Countries

India

Contacts

Public ContactDr. Vivek Maratha

Subharti Medical College and Hospitals

drvivekmaratha@yahoo.com9837035415

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026