Comparison of intrathecal bupivacaine with dexmedetomidine versus intrathecal levobupivacaine with dexmedetomidine for lower limb and lower abdominal surgeries

Comparison of intrathecal bupivacaine versus intrathecal levobupivacaine with dexmedetomidine as an adjuvant for lower limb and lower abdominal surgeries - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/097003

Enrollment

Registered

2025-11-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 3ml levobupivacaine + dexmedetomidine(5mcg) will be given to group LD and 3ml of levobupivacaine + dexmedetomidine(5mcg) will be given to group BD.: after giving spinal anaesthesia the

Eligibility

Inclusion criteria

Inclusion criteria: patient willing to participate in study and provide informed consent. ASA physical status 1 and 2. age between 18 to 60 years patient posted for surgery under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: participants with history of allergy to study drugs. participants with bleeding disorders, uncontrolled diabetic mellitus, cardiovascular, renal and liver disorders. local site infection, peripheral vascular disease. patients with pyschiatric disorder and on antipsychotic medications. pregnant women.

Design outcomes

Primary

Measure	Time frame
To compare intrathecal bupivacaine and dexmedetomidine versus intrathecal levobupivacaine and dexmedetomidine in terms of onset and duration of sensory and motor blockTimepoint: dermatomes levels will be tested every 2 min and sensory level is noted. Time to two segment sensory regression will be recorded. The motor dermatome level will be assessed using Modified Bromage scale. The time to reach Bromage scale 3 before surgery and Bromage 0 in post anaesthesia care unit (PACU) will be recorded.	—

Measure

Time frame

To compare intrathecal bupivacaine and dexmedetomidine versus intrathecal levobupivacaine and dexmedetomidine in terms of onset and duration of sensory and motor blockTimepoint: dermatomes levels will be tested every 2 min and sensory level is noted. Time to two segment sensory regression will be recorded. The motor dermatome level will be assessed using Modified Bromage scale. The time to reach Bromage scale 3 before surgery and Bromage 0 in post anaesthesia care unit (PACU) will be recorded.

—

Secondary

Measure	Time frame
To compare two drugs in terms of duration of analgesia hemodynamic parameter and any adverse effectsTimepoint: immediately after block, during the operation at 5, 10, 15,20,25, 30, and 60 min after spinal block, at the end of the procedure and every 60 min in the recovery room.	—

Countries

India

Contacts

Public ContactAnand Tippanna Talikoti

sapthagiri institute of medical sciences and research center

drttanand@yahoo.com9986093837

Outcome results