Health Condition 1: P289- Respiratory condition of newborn,unspecified
Conditions
Interventions
Intervention1: PEEP 7-8 cm of water: PEEP 7-8 cm of water via T piece resuscitator during delivery room resuscitation till stabilisation.
Control Intervention1: PEEP 5-6 cm of water: PEEP 5-6 cm of wa
Sponsors
AIIMS Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: 1.Inborn preterm infants less than 32 weeks gestation requiring resuscitation in delivery room.
Exclusion criteria
Exclusion criteria: 1.Antenatally diagnosed major congenital anomalies or chromosomal disorders. 2.Infants born via MTP. 3.Hydrops fetalis or pulmonary hypoplasia. 4.Preterm new born with surgical conditions. 5.Antenatal diagnosis of conditions resulting in poor prognosis. 6.Peri viable new borns
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Incidence of endotracheal intubation within 72 hrs of birth 2.trends of oxygenation(modified oxygenation index SpO2/FiO2) in first 72 hrs of birth 3.Incidence of hypoxic respiratory failure in first 72 hrs of birth in mechanically ventilated new bornTimepoint: At 2,4,6 and then 6 hourly till 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Need for surfactant replacement therapy in first 72 hrs. 2.CPAP failure rate in first 72 hrs after CPAP therapy initiation in NICU. 3.Duration of mechanical ventilation. 4.Duration of respiratory support. 5.Duration of oxygen 6.Hemodynamic compromise in the first 72hrs 7.Rates of BPD at 36 weeks PMA. 8.Incidence of airleak syndromes. 9.Preterm mortality & morbidities like IVH 3/4 , NEC ,ROP, PVL, Culture proven sepsis , duration of NICU stay. 10. Delivery room clinical parametersTimepoint: At 2,4,6 & then 6 hourly. 3days, 7 days, 14 days & 28 days or at discharge. | — |
Countries
India
Contacts
Public ContactDr Chetan Khare
AIIMS Bhopal
Outcome results
None listed