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Study of blood cell ratios as markers of infection severity in patients with sepsis

A comparative study of Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio, and mean platelet volume to platelet count ratio as biomarkers in patients with sepsis assessed using qSOFA and APACHE2 criteria - SEPBIOMARK

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/096981
Enrollment
70
Registered
2025-11-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

Metrounited Healthcare
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: any patient with age more than 18 yr and in sepsis

Exclusion criteria

Exclusion criteria: age less than 18 years corticosteroid therapy antibiotics use before admission hematological disorder malignant disease chemotherapy or radiotherapy 1 month before

Design outcomes

Primary

MeasureTime frame
Predictive performance of baseline Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio, and Mean platelet volume to platelet count ratio for 28 day all cause mortality in patients with sepsisTimepoint: baseline biomarker measurements- within 24 hours of hospital admission primary endpoint assessment- 28 days after enrolment—

Secondary

MeasureTime frame
28 day mortality OR ICU admission OR need for vasopressors / mechanical ventilation can also be predictedTimepoint: 28 days—

Countries

India

Contacts

Public ContactDr Shubham deepak gonjari

Metrounited healthcare, shivamogga

drpruthvibc@gmail.com9448064080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026