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Study on the Effect of IV Ephedrine on Blood Pressure and Heart Rate Changes During Kidney Stone Surgery Under Spinal Anaesthesia

A Randomized Controlled Study to Evaluate the Effect of Iv Ephedrine on Hemodynamic Variations in Patients Undergoing Percutaneous Nephrolithotomy Under Spinal Anaesthesia at sms medical college jaipur - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096978
Enrollment
66
Registered
2025-11-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: IV Ephedrine: Patients in the intervention group will receive Ephedrine 0.1 mg/kg intravenous (IV) bolus immediately after administration of spinal anaesthesia, followed by monitoring o

Sponsors

Department of Anaesthesia,Sawai Man Singh Medical College and Attached Hospital Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients posted for PCNL elective surgery. 2. Patients those are willing to participate in the study. 3. Aged 18-60 years. 4. American Society of Anaesthesiologists (ASA) classes I and II. 5. Body mass index less than 35kg/m2.

Exclusion criteria

Exclusion criteria: 1. Patient those are part of any other study. 2. Coagulopathy, patients with skeletal deformities. 3. History of systemic disease, mental illness, drug abuse. 4. History of allergy to any of the drugs used during the study.

Design outcomes

Primary

MeasureTime frame
Mean Heart Rate in beats per minute Mean Systolic Blood Pressure in mmhg Mean Diastolic Blood Pressure in mmhg Mean requirement of vasopressors Proportion of cases with adverse effects like bradycardia hypotension nausea vomitingTimepoint: Every 3 minutes for 15 minutes and 5 minutes thereafter—

Secondary

MeasureTime frame
Bradicardia & vasopressor requirementTimepoint: Every 3 minutes for 15 minutes & 5 minutes thereafter—

Countries

India

Contacts

Public ContactDr Vinod Sharma

SMS MEDICAL COLLEGE JAIPUR

aiims.priyanka@gmail.com9309482150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026