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A study comparing Intravenous and nebulised dexmedetomidine to reduce stress during intubation and sore throat after surgery under general anaesthesia: A Randomised Study

A Randomised prospective study to see the comparison of Intravenous versus nebulised dexmedetomidine for intubation induced sympathoadrenal stress response & post operative sore throat attenuation in patient undergoing General anaesthesia - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096951
Enrollment
100
Registered
2025-11-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: PCS-

Interventions

Intervention1: Intravenous dexmedetomidine infusion 1microgram/kg over 10 minutes: To evaluate the haemodynamic response in one group during endotracheal intubation after using 1microgram/kg over 10 m

Sponsors

Department of Anaesthesiology first floor new ot JLN medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1&2 Mallampati 1 and 2 Age 18-60 yrs

Exclusion criteria

Exclusion criteria: ASA 3 and above Mallampati 3 and 4 Allergic to drug Obese

Design outcomes

Primary

MeasureTime frame
To see haemodynamic response During endotracheal intubation using iv and nebulised dexmedetomidine and compare efficacy in blunting the symapathoadrenal response.Timepoint: To see haemodynamic response During endotracheal intubation using iv and nebulised dexmedetomidine and compare efficacy in blunting the symapathoadrenal response—

Secondary

MeasureTime frame
To evaluate 24 hr analgesic consumption in both groups, To compare the postoperative sore throatTimepoint: To evaluate 24 hr analgesic consumption in both groups, To compare the postoperative sore throat in 24 hours—

Countries

India

Contacts

Public ContactDrVeena Patodi

JLN medical college & hospital

veenapatodi@gmaiil.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026