Comparison of medicines given before surgery (ranitidine and pantaprazole) to check how they affect stomach acid and fluid levels

Comparision of inj. Ranitidine 50mg, Inj. Ranitidine 100mg, inj. Pantaprazole 40mg preoperatively in assessment of gastric volume and pH in elective cases - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/096948

Enrollment

Registered

2025-11-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z530- Procedure and treatment not carried out because of contraindication

Interventions

Control Intervention1: Injection Pantoprazole: 40mg iv 1hour and 2 hour before elective surgery Control Intervention2: Injection Ranitidine: 100mg iv 1 hour and 2 hour before elective surgery Control

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing surgery under sedation or GA. Pregnant females. Refusal to participate.

Exclusion criteria

Exclusion criteria: Allergy and contraindication to pantaprazole and Ranitidine. Pregnant women

Design outcomes

Primary

Measure	Time frame
To assess the efficacy of the drugs in reducing gastric volume and aspiration RiskTimepoint: Gastric volume will be assessed through usg at 1 hour and 2 hour after giving drug preoperatively	—

Secondary

Measure	Time frame
Change in gastric volumeTimepoint: Assessment at 1 hour & 2 hour preoperatively	—

Countries

India

Contacts

Public ContactDr Anil kumar verma

GSVM medical college

aribainam1998@gmail.com9517580555

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026