Health Condition 1: G30- Alzheimers disease
Conditions
Interventions
Intervention1: Transcranial Direct current stimulation (tDCS): The Anode electrode and the cathode electrode will be placed over the left dorsolateral prefrontal cortex and over the right supraorbita
Sponsors
SELF
Eligibility
Inclusion criteria
Inclusion criteria: A : Patients diagnosed with Alzheimer s disease according to standardized diagnostic criteria (ICD-11). B : Patients who will give informed consent. C : Patients between the ages of 60 years and 80 years. D : Patients on Donepezil for a minimum of 4 weeks with MMSE Score between 18-23.
Exclusion criteria
Exclusion criteria: A : Age below 60 years and above 80 years B : Patients with a history of significant neurological disorders other than dementia (e.g. Traumatic Head Injury, epilepsy). C : Individuals with severe psychiatric conditions (e.g., schizophrenia, Mental retardation, Mood Disorders) D : Individual who was previously diagnosed with Wernicke s Koraskoff Psychosis E : Those with contraindications to tDCS (transcranial direct current stimulation), such as implanted electronic devices. F : Inability to undergo the required cognitive assessments due to language barriers, severe sensory impairments, or other factors affecting comprehension or communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of tDCS on cognitive function in patients of alzheimers disease Scales : ACE-III,MMSE,CGI and side effectsTimepoint: At Baseline, after 4 weeks [total 40 sessions (twice daily 5 days per week x 4 week)] and after 8 week. | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactProf Dr Suvendu Narayan Mishra
INSTITUTE OF MEDICAL SCIENCES (IMS) AND SUM HOSPITAL
Outcome results
None listed