None listed
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Bill and Melinda Gates Foundation
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients who come to Christian Medical College Vellore, for hepatobiliary resections for certain disease conditions such as hepatobiliary carcinoma, liver metastasis secondary to other cancers or benign conditions requiring resections such as hydatid cystgallbladder polyps, hepatolithiasis will be recruited in the study. Among these study patients who reside in malaria endemic regions such as Jharkhand, Uttar Pradesh, West Bengal will be consented to participate in the study
Exclusion criteria
Exclusion criteria: We will not include patients on immunosuppression prior to resection for over 6 months patients with liver cirrhosis acute or chronic liver disorders such as hepatitis C and hep B with cirrhosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To characterize the T resident memory cells from the liver biopsy samples by flow cytometry To assess the T cell receptor sequencing data among Plasmodium falciparum-exposed individualsTimepoint: 24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine an assay cutoff for malarial antibodies.Timepoint: 24 months | — |
Countries
India
Contacts
Public ContactRavish Raju
Christian Medical College Vellore
Outcome results
None listed