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A Study Comparing The Effects Of Two Pain Medications Remifentanil And Fentanyl On Blood Pressure, Heart Rate And Recovery After Brain Surgery.

Comparison Of Effects Of Remifentanil And Fentanyl On Hemodynamics And Recovery In Patients Undergoing Elective Craniotomy Under General Anaesthesia ,A Prospective Observational Single Center Double Blind Study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096892
Enrollment
100
Registered
2025-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D496- Neoplasm of unspecified behavior of brain

Interventions

Intervention1: Fentanyl Group: Group F (Fentanyl group): Patients will receive Fentanyl as the primary opioid analgesic during anesthesia. In Fentanyl group 60cc syringe will be loaded with 40 cc no

Sponsors

P.D.Hinduja Hospital And Medical Research Center, Mahim
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age :18-80 Years Both Male And Non Pregnant Females Patients ASA I-III Glassgow Coma Scale 15/15

Exclusion criteria

Exclusion criteria: Refusing to participate Age less than 18 and more than 80 years BMI more than 35Kg/m2 Pregnant females Allergy to opioids ASA IV-V Emergency surgery

Design outcomes

Primary

MeasureTime frame
1.To compare effects of Remifentanil and Fentanyl on intraoperative hemodynamics . 2. To compare effects of Remifentanil and Fentanyl on recovery.Timepoint: Mean Rate Pressure Product ,Systolic Blood Pressure ,Diastolic Blood Pressure,Heart Rate,Mean Arterial Presssure at points of maximal stimuli such as Intubation,Pinning, Incision, Craniotomy,Dural Incision ,Extubation noted at 0min, 1min and 5 min.

Secondary

MeasureTime frame
Secondary objectives of the study is to assess the requirement of additional analgesics in immediate post operative period and to see if any complications.Timepoint: Analgesic requirement post extubation at 0min,10min,20min.

Countries

India

Contacts

Public ContactDr Renukadevi Tulshidas Shilimkar

Dept. of Neuroanaesthesia, P.D.Hinduja Hospital and Medical Research Centre,Mahim

shwetalgoraksha@gmail.com9819570713

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026