Health Condition 1: O098- Supervision of other high risk pregnancies
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Aiims Bibinagar
Eligibility
Inclusion criteria
Inclusion criteria: Singleton pregnancies with estimated fetal weight below the 3rd centile or below 10th percentile for gestational age, with abnormal fetal Doppler in umbilical artery, middle cerebral artery, or cerebroplacental ratio.
Exclusion criteria
Exclusion criteria: 1. Major fetal structural or chromosomal abnormalities, 2. placentas with tissue quality insufficient for histologic assessment, and 3. cases without reliable gestational age or cord/neonatal hypoxia sampling
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the correlation between syncytial knot index and villous pathology with fetal Doppler abnormalities in pregnancies complicated by fetal growth restriction (FGR).Timepoint: To evaluate the correlation between syncytial knot index and villous pathology with fetal Doppler abnormalities in pregnancies complicated by fetal growth restriction (FGR). | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the relationship between syncytial knot index & neonatal hypoxia markers, including umbilical cord arterial pH, base excess, & lactate levels.Timepoint: At delivery;To determine the correlation between villous pathology and neonatal acid-base statusTimepoint: At Birth;To explore whether placental histopathological findings can serve as postnatal markers supporting the severity of antenatal Doppler abnormalities in FGR.Timepoint: At Birth | — |
Countries
India
Contacts
Public ContactMishu Mangla
All India Institute of Medical Sciences
Outcome results
None listed