Effect of Drug named Dexmedetomidine on Blood Sugar Levels in Diabetic Patients During and After Lower Limb Surgery Under Spinal Anaesthesia

Role of Dexmedetomidine on Perioperative Glycemic control in Diabetic patient undergoing lower limb surgery under spinal anaesthesia A Prospective Randomized Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/096873

Enrollment

Registered

2025-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Dexmedetomidine Infusion: Dexmedetomidine infusion @ 0.6 mcg/kg/hr after induction with spinal anesthesia upto T8 Dermatome Control Intervention1: Normal Saline Infusion: Normal saline

Eligibility

Inclusion criteria

Inclusion criteria: Individuals with DM of age 20-65 years scheduled for lower limb surgery under spinal anesthesia Patient classified as ASA grade 2 and grade 3

Exclusion criteria

Exclusion criteria: Patient who didn’t give consent Patient who are allergic to study drug Pregnant females

Design outcomes

Primary

Measure	Time frame
Change in Serum blood glucose levelTimepoint: Preoperative(T0) 1hr post incision (T1) 2hr Post incision (T2) 3hr Post incision (T3) 6hr post incision (T6) 12hr post incision (T12) 24hr post incision (T24)	—

Secondary

Measure	Time frame
Change in salivary cortisol level Intraoperative Heart rate, Mean arterial Pressure Time to first rescue analgesiaTimepoint: Preoperative salivary cortisol (T0) 1hr post incision (T1) 2hr Post incision (T2) 3hr Post incision (T3) 6hr post incision (T6)	—

Countries

India

Contacts

Public ContactOppuri Sai Sujinesh Reddy

AIIMS

jaiprakash.anesth@aiimsbhopal.edu.in9425609647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026