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Cooling Therapy and Saline Flush to Prevent Vein Inflammation in Cancer Patients Receiving Chemotherapy

A study to evaluate the effectiveness of Cryotherapy with Isotonic Saline Flush on Phlebitis Incidence among Chemotherapy Patients admitted in a Tertiary Care Hospital. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096870
Enrollment
62
Registered
2025-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I809- Phlebitis and thrombophlebitis ofunspecified site

Interventions

Intervention1: Cryotherapy with Isotonic Saline Flush: Cryotherapy: Ice pack gel application of temperature zero to 4 degree Celsius which is wrapped on double layered towel on local intravenous canul

Sponsors

Shinoj T
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients (aged 18 and above) receiving chemotherapy. Patients who are willing to participate and provide informed consent. Patients with peripheral IV catheters in place for chemotherapy administration.

Exclusion criteria

Exclusion criteria: Patients with a history of vascular conditions that may independently predispose them to phlebitis (e.g., varicose veins, thrombophlebitis). Patients with pre-existing phlebitis at the time of admission. Patients who are unable to provide informed consent or have cognitive impairments preventing them from participating. Patients who are receiving central venous catheters for chemotherapy, as these may reduce the risk of phlebitis from peripheral IV administration. Patient who are hypothermic. Patients who are hypersensitive to cryotherapy or saline infusion.

Design outcomes

Primary

MeasureTime frame
Reduction in the incidence of phlebitis among those patients who receive cryotherapy with isotonic saline flush as compared routine interventionTimepoint: Day 1, Day 2, and Day 7

Secondary

MeasureTime frame
Identify the association between selected parameters and the incidence of phlebitis among patients receiving chemotherapyTimepoint: Day 1, Day 2, and Day 7

Countries

India

Contacts

Public ContactMr Shinoj T

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, MANGALAGIRI

sudheendra@aiimsmangalagiri.edu.in7984064399

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026