Total intraoperative fentanyl consumption comparison in modified radical mastectomy patients under general anaesthesia

Comparison of surgical pleth index guided analgesia with conventional analgesia technique for total intraoperative fentanyl consumption in patients undergoing modified radical mastectomy under general anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/096858

Enrollment

Registered

2025-11-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Surgical pleth index guided analgesia: Surgical pleth index guided analgesia will be given and intraoperative fentanyl consumption will be noted Control Intervention1: Conventional anal

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 or 2 BMI between 18.5 and 30 kg/m2

Exclusion criteria

Exclusion criteria: Allergy or hypersensitivity to fentanyl or study drugs Chronic opioid use or analgesic dependence Cardiovascular instability Autonomic dysfunction or peripheral vascular disease Severe hepatic or renal impairment Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame
Total intraoperative fentanyl consumption in microgram will be measured in surgical pleth index guided analgesia technique and conventional analgesia techniqueTimepoint: Baseline HR and SBP will be noted then intraoperative HR,SBP and fentanyl total doses will be noted	—

Secondary

Measure	Time frame
1.Postoperative pain score in the form of numerical rating score(NRS) in recovery 2.Incidence of post operative nausea vomiting in recoveryTimepoint: After the surgery is over that is post operative	—

Countries

India

Contacts

Public ContactAkhilesh gupta

ABVIMS and Dr RML Hospital

Drakhileshgupta@gmail.com9810685426

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026