PREDICT DELIRIUM TRIAL :Prevention of Delirium in Critically ill Patients by comparing Non-Pharmacological versus Pharmacological Techniques -A Randomised Controlled trial

A Randomised Controlled Trial on Non-Pharmacological versus Pharmacological Interventions for Prevention of Delirium among Critically ill patients. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/11/096847

Enrollment

Registered

2025-11-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F59- Unspecified behavioral syndromes associated with physiological disturbances and physical factors

Interventions

Intervention1: Pharmacological techniques: Pharmacological group : Tab.Melatonin (3mg)per oral once a day (especially in the night) during ICU stay or Inj.DEXMEDOTOMIDINE (2-7mcg/hr) IV infusion tit

Eligibility

Inclusion criteria

Inclusion criteria: 1.minimum length of stay more than 24hrs 2.Awake intubated patients

Exclusion criteria

Exclusion criteria: 1. Poor GCS ,Prior Dementia and cognitive impairement 2. already diagnosed encephalopathy 3.Not coopertive

Design outcomes

Primary

Measure	Time frame
1.Comparing the effectiveness of Non-pharmacological versus pharmacological interventions for prevention of delirium among critically ill patients 2. To Estimate the frequency of occurence of Delirium in ICUTimepoint: 1.During ICU Stay- 0,24hrs,48hrs,72hrs and 2. During discharge from ICU	—

Secondary

Measure	Time frame
Duration of Mechanical ventilation length of stay in ICU & Hospital stay incidence of inadvertent catheter removal ICU readmissions All cause 30day mortalityTimepoint: During ICU stay- 24hrs,48hrs,72hrs During discharge from ICU 30 days telephonically	—

Countries

India

Contacts

Public ContactVanitha N

NABH -Accrediated hospital

vp10vanitha@gmail.com9916872121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026