Health Condition 1: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
Intervention1: Injection Thiopentone Sodium: Thiopentone Sodium 3 to 5 mg per kg intravenous bolus given as an induction agent before each session of modified electroconvulsive therapy administered as
Sponsors
Pacific Medical College and Hospital Udaipur
Eligibility
Inclusion criteria
Inclusion criteria: The Patients relative gives consent Adult patients of either sex with an ASA grade of I or II Age range of 18 to 60 years ECT indication- Patients diagnosed with psychiatric conditions for which MECT is indicated.
Exclusion criteria
Exclusion criteria: Patients relative refusal of the MECT procedure Known allergy to the study drug ASA grade more than II History of cardiovascular respiratory or neurological disorders Intracranial lesions or increased intracranial pressure Pregnancy or lactation Epilepsy Neuromuscular disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effifacy of Thiopentone, Propofol, and mixture of Propofol and Ketamine on the duration of seizures induced during Modified ECT.Timepoint: To compare the efficacy of Thiopentone, Propofol, and a mixture of Propofol and Ketamine on the duration of seizures induced during Modified ECT at baseline, 1min, 5min, 10min, 15min, 20min | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess hemodynamic parameters like Heart rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean arterial pressure Agitation score Return of spontaneous ventilationTimepoint: Assess hemodynamic parameters[ Heart rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean arterial pressure Agitation score Return of spontaneous ventilation at baseline 1 min, 5 min, 10min, 15min, 20min | — |
Countries
India
Contacts
Public ContactDr Rajendra Solanki
Pacific Medical College and Hospital
Outcome results
None listed