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A randomised study to find which is more effective for palmoplantar psoriasis: emollients with topical steroids or emollients with oral appremilast

Effectiveness of emollients with topical steroids vs emollients with oral apremilast in the management of palmoplantar psoriasis- A Randomised Controlled Trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096810
Enrollment
40
Registered
2025-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L408- Other psoriasis

Interventions

Intervention1: Emollient with topical steroids (0.1% mometasone furoate with 3% salicylic acid cream.: Participants will apply the emollients over the entire affected area twice daily throughout the s

Sponsors

Dr K V Pushpanjali
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults aged 18 to 65 years. 2. Diagnosed with palmoplantar psoriasis (with or without nail involvement). 3. DLQI score greater than or equal to 5. 4. Patients who provide written informed consent

Exclusion criteria

Exclusion criteria: Patients with generalised Psoriasis or psoriatic arthritis. Pregnant or lactating women. Patients with liver or kidney dysfunction, active tuberculosis or immunosuppressive conditions Recent use (within 4 weeks) of systemic anti-Psoriatic drugs or biologics Hypersensitivity to apremilast or corticosteroids

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness of topical emollients with topical steroids versus emollients with oral apremilast in adults suffering from palmoplantar psoriasisTimepoint: Day 0 Wk 4 Wk 8 Wk 12 Wk 24

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Gopalakrishnan K

Chettinad Hospital And Research Institute

dermdrgopalakrishnan@gmail.com04447428101

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026