Skip to content

Which sedation method helps patients recover faster after egg retrieval for IVF?

Comparative study on the effects of two different techniques of combining dexmedetomidine and ketamine on post operative recovery time in patients undergoing oocyte retrieval: a randomised controlled pilot study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/11/096809
Enrollment
60
Registered
2025-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N970- Female infertility associated withanovulation Health Condition 2: N979- Female infertility, unspecified

Interventions

Intervention1: In Group A, patients will receive a maintenance dose of 0.7 mcg/kg/hr dexmedetomidine, titrated to maintain sedation: In Group A, patients will receive an induction dose of 1 mcg/kg dex

Sponsors

Aditi Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women undergoing elective oocyte retrieval. ASA I & II patients. Age between 18 years to 40 years. Patients willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Patients who deny consent will not be included in the study. ASA III and ASA IV. Past history of allergy to dexmedetomidine and ketamine. Chronic sedative and opioid use

Design outcomes

Primary

MeasureTime frame
To compare the post operative recovery time measured from procedure end to Modified Aldrete score more than equal to 9 at 10mis, 20 mins and 30 minsTimepoint: To compare the post operative recovery time measured from procedure end to Modified Aldrete score more than equal to 9 at 10 mins,20 mins and 30 mins

Secondary

MeasureTime frame
To evaluate & compare hemodynamic stability in terms of heart rate & blood pressure at various time intervals intraoperatively. To assess pain score (VAS Score) on complete recovery, at thirty minutes & at sixty minutes from the end of the procedure. To evaluate the need for rescue analgesia. To investigate the adverse effects like nausea, vomiting, dizziness, hallucinations during recovery time. Timepoint: complete recovery, at 30 minutes & at 60 minutes from the end of the procedure

Countries

India

Contacts

Public ContactJimna Joy

Armed Forces Medical College, Pune

jjoshi00@gmail.com9644838766

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026