Health Condition 1: J342- Deviated nasal septum Health Condition 2: 8- Other Procedures Health Condition 3: H040- Dacryoadenitis Health Condition 4: J324- Chronic pansinusitis Health Condition 5: J330- Polyp of nasal cavity Health Condition 6: J343- Hypertrophy of nasal turbinates Health Condition 7: J339- Nasal polyp, unspecified Health Condition 8: J320- Chronic maxillary sinusitis Health Condition 9: J324- Chronic pansinusitis Health Condition 10: J341- Cyst and mucocele of nose and nasal sin
Conditions
Interventions
Intervention1: Reducing stress response to laryngoscopy and endotracheal intubation: To compare different doses of nebulized dexmedetomidine and nebulized fentanyl in attenuation of hemodynamic stress
Sponsors
Karnataka medical college and research institute Vidyanagar Hubli
Eligibility
Inclusion criteria
Inclusion criteria: AMERICAN SOCIETY OF ANAESTHESIOLOGISTS [ASA]physical status classification I and II Patients undergoing elective nasal surgeries under general anaesthesia Patients giving valid informed written consent
Exclusion criteria
Exclusion criteria: Patients with neurological disorders , uncontrolled hypertension, uncontrolled Type 2 Diabetes mellitus,Ischemic heart disease, Chronic obstructive pulmonary disease, Bronchial asthma, Bleeding disorders, Psychiatric illness and nasal trauma . Patients with history of allergy to opiods and local anaesthetic agents and dexmedetomidine . Pregnant , lactating mothers. Morbidly obese patients BMI more than 40 kg / m²
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of nebulised dexmedetomidine 1 mcg/kg ,1.5 mcg/kg and fentanyl 1 mcg/kg in attenuating hemodynamic stress response to laryngoscopy and endotracheal intubation in terms of changes in systolic blood pressure (SBP),Diastolic blood pressure (DBP),mean blood pressure (MBP)and heart rate (HR) in patients undergoing elective nasal surgeries.Timepoint: Nebulisation will be given 10min before shifting to operation theatre. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess postoperative pain using Visual Analog Scale immediately after extubation i.e 0hrand 1hr,3hr,6hr,12hr post surgery and extubationTimepoint: 0hr , 1hr, 3hr, 6hr, 12hr post surgery and extubation.;To assess postoperative Ramsay sedation score immediately after extubation i.e 0hr and 1hr, 3hr,6hr, 12hr post surgery and extubation.Timepoint: 0hr, 1hr, 3hr, 6hr, 12hr post surgery and extubation. | — |
Countries
India
Contacts
Public ContactDR PRIYA N
KMC-RI Hubli
Outcome results
None listed