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HOW GALLBLADDER WALL THICKNESS AND C-REACTIVE PROTEIN LEVELS AFFECT OUTCOMES IN LAPAROSCOPIC CHOLECYSTECTOMY

Correlation Of Pre-operative Gallbladder Wall Thickness And C-Reactive Protein With Operative And Post Operative Outcomes Of Laparoscopic Cholecystectomy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/11/096745
Enrollment
45
Registered
2025-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis Health Condition 2: K82- Other diseases of gallbladder Health Condition 3: K819- Cholecystitis, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Jawaharlal Nehru Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing laparoscopic cholecystectomy Preoperative ultrasonographic measurement of gallbladder wall thickness (GBWT)and serum C-reactive protein (CRP) level assessment Provision of informed written consent

Exclusion criteria

Exclusion criteria: Gallbladder perforation diagnosed preoperatively Choledocholithiasis Pregnancy Recent trauma Active malignancy Concurrent other infections or sepsis Patient on Anti-inflammatory drugs Uncontrolled systemic comorbidities Patients unwilling or withdrawing consent

Design outcomes

Primary

MeasureTime frame
1)To asses the pre-operative evaluate gall bladder thickness and C-reactive protein. 2) To evaluate the association of preoperative gallbladder wall thickness (GBWT)) with operative difficulty (using Nassar criteria), operative and postoperative outcomes in patients undergoing laparoscopic cholecystectomy. 3) To evaluate the association of C-reactive protein (CRP) levels with operative difficulty (using Nassar criteria), operative and postoperative outcomes in patients undergoing laparoscopic cholecystectomy. Timepoint: Pre-op US GB wall thickness: within 7 days prior to surgery (document exact interval). Baseline CRP: within 48–72 hours prior to surgery . Follow-ups: after 7–10 days and 30 ±7 days (for post operative outcomes).—

Secondary

MeasureTime frame
1) To determine the predictive value of combined GBWT and CRP in anticipating intraoperative complexity. 2) To analyze the correlation of GBWT and CRP levels with postoperative complications like wound infection, bile leak, jaundice. Timepoint: Pre-operative: GBWT USG within 7 days before surgery ; CRP within 24-48 hr pre-op Intra-operative: real-time recording (during surgery). Post-op Day 1 (POD1) Post-op Day 3 (POD3) Post-op Day 7 (±2 days) Post-op Day 30 (±7 days)—

Countries

India

Contacts

Public ContactDr Pooja Batra

Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research

drpoojabatra16@gmail.com9881165415

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026