Role of a sedative in caesarean delivery.

Effect of intravenous ketamine infusion on obstetric quality of recovery score in patient undergoing cesarean delivery after spinal anesthesia: A randomized, triple-blinded, controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096733

Enrollment

142

Registered

2025-10-31

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Group K: 0.3 mg/kg ketamine in 10 ml of saline bolus followed by 0.1 mg/kg/hr infusion Control Intervention1: Group C: 1O ml saline bolus followed by infusion

Eligibility

Inclusion criteria

Inclusion criteria: Female patients and full term, between 21 and 41, with ASA I, II, III, and undergoing elective cesarean section.

Exclusion criteria

Exclusion criteria: 1) Twins and preterm birth 2) Hypertensive and pre-eclampsia patient 3) Morbidly obese patient 4) Spinal anesthesia contraindication because the patient refused, severe mitral or tricuspid stenosis and local infection

Design outcomes

Primary

Measure	Time frame
Effect of intravenous ketamine infusion on obstetric quality of recovery scoreTimepoint: 24 hours	—

Secondary

Measure	Time frame
Hemodynamic parameters (MAP and HR)Timepoint: 15 minutes, 30 minutes, 45 minutes, 60 minutes;Ramsay Sedation ScoreTimepoint: 5 minutes, 10 minutes, 20 minutes, 30 minutes, 40 minutes;VAS ScoreTimepoint: 4 hours, 8 hours, 12 hours, 16 hours, 24 hours;APGAR ScoreTimepoint: 1 minute, 5 minutes	—

Countries

India

Contacts

Public ContactSwati

Indira Gandhi Institute of Medical Sciences, Patna

Swatipgi2006@gmail.com9113463130

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026