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A Study on How Moving Patients Early During Serious Illness, Compared to Regular ICU Care, Helps Them Recover Strength and Function, and Prevents Muscle Loss.

Effect Of Protocolised Early Mobilisation Versus Routine Icu Care On Functional Outcome And Sarcopenia In Critically Ill Patients - A Prospective Randomised Control Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096710
Enrollment
60
Registered
2025-10-31
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M625- Muscle wasting and atrophy, not elsewhere classified

Interventions

Intervention1: Protocolised mobilisation: Mobilisation will be initiated within 48 hours of ICU admission, and progressed stepwise according to patient’s clinical status and tolerance Level I (Unconsc

Sponsors

Abhijith S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ICU patients who are expected to stay in ICU for more than 48 hours and able to initiate mobilization within 48 hours of ICU admission

Exclusion criteria

Exclusion criteria: Hemodynamic instability, requiring more than 0.8mcg per hour of noradrenaline or comparable inotropic support, severe pulmonary hypertension, bradycardia requiring treatment or dependent rhythm with pacemaker, tachyarrhythmia ventricular rate more than 120 beats per minute, cardiac ischemia Fio2 requirement more than 60 percent , PEEP more than 10 , prone positioning Polytrauma with traumatic brain injury with risk of raised intracranial pressure , unstable spine injuries, unstable pelvis or long bone fractures, blunt or open trauma chest and abdomen with active bleeding risk Active neurological concern , RASS score other than -2 to +1, active management of elevated intracranial pressure, uncontrollable seizures Patients with devices such as Femoral IABP or ECMO or pulmonary artery catheter or another cardiac monitoring device or femoral sheaths Previously bedridden patients or pre-existing neuromuscular disease or severe physical disability Any other contraindication to mobilisation

Design outcomes

Primary

MeasureTime frame
Functional status at ICU discharge: measured by ICU mobility scale Change in rectus femoris muscle thickness and cross-sectional area Timepoint: ICU mobility scale - at ICU admission and discharge from icu Change in rectus femoris muscle thickness and cross-sectional area - at ICU admission, day 3, day 7 , day of discharge from ICU

Secondary

MeasureTime frame
ICU length of stay Ventilator free days Complications related to mobilisation Timepoint: ICU length of stay - at discharge from icu Ventilator free days - at discharge from icu Complications related to mobilisation - on each day during icu stay

Countries

India

Contacts

Public ContactAbhijith S

Jubilee mission medical college and research institute

drpauljohn@gmail.com9447991902

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026