Health Condition 1: M625- Muscle wasting and atrophy, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ICU patients who are expected to stay in ICU for more than 48 hours and able to initiate mobilization within 48 hours of ICU admission
Exclusion criteria
Exclusion criteria: Hemodynamic instability, requiring more than 0.8mcg per hour of noradrenaline or comparable inotropic support, severe pulmonary hypertension, bradycardia requiring treatment or dependent rhythm with pacemaker, tachyarrhythmia ventricular rate more than 120 beats per minute, cardiac ischemia Fio2 requirement more than 60 percent , PEEP more than 10 , prone positioning Polytrauma with traumatic brain injury with risk of raised intracranial pressure , unstable spine injuries, unstable pelvis or long bone fractures, blunt or open trauma chest and abdomen with active bleeding risk Active neurological concern , RASS score other than -2 to +1, active management of elevated intracranial pressure, uncontrollable seizures Patients with devices such as Femoral IABP or ECMO or pulmonary artery catheter or another cardiac monitoring device or femoral sheaths Previously bedridden patients or pre-existing neuromuscular disease or severe physical disability Any other contraindication to mobilisation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional status at ICU discharge: measured by ICU mobility scale Change in rectus femoris muscle thickness and cross-sectional area Timepoint: ICU mobility scale - at ICU admission and discharge from icu Change in rectus femoris muscle thickness and cross-sectional area - at ICU admission, day 3, day 7 , day of discharge from ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU length of stay Ventilator free days Complications related to mobilisation Timepoint: ICU length of stay - at discharge from icu Ventilator free days - at discharge from icu Complications related to mobilisation - on each day during icu stay | — |
Countries
India
Contacts
Jubilee mission medical college and research institute