Health Condition 1: Z379- Outcome of delivery, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Karnataka medical college and research instituteVidyanagarHubli
Multidisciplinary Research Unit
Eligibility
Inclusion criteria
Inclusion criteria: 60 pregnant mothers undergoing elective C-section preferably balanced between general and spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Emergency C- section
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the association between anaesthesia-related parameters and DNA methylation patterns in selected neonatal genes related to stress response, neurodevelopment, and immune function.Timepoint: Baseline at the time of birth | — |
Secondary
| Measure | Time frame |
|---|---|
| - To describe the methylation status of specific genes (e.g., NR3C1, BDNF, OXTR, IL6, DNMT3A) in neonates born via elective C-section under anaesthesia.Timepoint: Baseline At time of delivery;- To explore correlations between neonatal methylation levels & clinical factors such as birth weight, APGAR scores & maternal hemodynamic parameters during anaesthesia.Timepoint: Baseline At the time of delivery. | — |
Countries
India
Contacts
Public ContactMilon Vasant Mitragotri
Karnataka Medical College and research Institute
Outcome results
None listed