Health Condition 1: L814- Other melanin hyperpigmentation
Conditions
Interventions
Intervention1: Combination Peel: The participants of Group- CP will be treated with a combination peel, consisting of glycolic acid (33%), kojic acid (7%), lactic acid (6%), citric acid (5%), and sali
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Patients with a clinical diagnosis of POM aged 18 to 50 years who had not taken any treatment for the same in the past 6 months
Exclusion criteria
Exclusion criteria: 1.Allergy/hypersensitivity to any of the components of the combination peel or PDRN 2.Pregnant and lactating women 3.Active skin infections at the site of treatment 4.Patients with unrealistic expectations 5.Botox injection or any other procedures at the treatment site in the past 6 months 6.Systemic diseases and immunosuppression
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in periorbital pigmentation assessed by the Periorbital Hyperpigmentation Grading Scale (Sheth et al.) from baseline to 4 weeks after the final treatment session (Week 16).Timepoint: After 16 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in melanin and erythema index measured using the Dermacatch Pigment and Erythema Analyzer, dermoscopic improvement in pigmentary and vascular components assessed with the FotoFinder Video Dermoscope, photographic improvement evaluated by a blinded dermatologist using the Physician Global Assessment (PGA) scale, patient satisfaction measured using the Visual Analogue Scale (VAS; 0–10), and documentation of adverse events in terms of type, frequency, and severity, all assessed from baseline to 4 weeks after the final treatment session.Timepoint: After 16 weeks | — |
Countries
India
Contacts
Public ContactDr Chaithra Shenoy
CUTIS Academy of Cutaneous Sciences
Outcome results
None listed