A clinical trial to compare the efficacy of Carbetocin and Oxytocin in preventing post partum haemorrhage in elective caesarean sections

A Open labelled Randomised controlled trial to compare the efficacy of Carbetocin and Oxytocin in preventing post partum haemorrhage in uncomplicated elective caesarean sections at a tertiary care centre in Telangana - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096663

Enrollment

200

Registered

2025-10-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: INJ.CARBETOCIN: UTEROTONIC AGENT 100mcg IV in 10ml NS over 10 min Control Intervention1: OXYTOCIN: UTEROTONIC AGENT 10IU in 500mlNS

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women 37 weeks of gestation Age 18 to 45 years Uncomplicated elective caesarean section Singleton pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To estimate the amount of intra operative blood loss in uncomplicated elective caesarean sectionsTimepoint: To estimate the amount of intra operative blood loss after placental delivery in uncomplicated elective caesarean sections	—

Secondary

Measure	Time frame
Estimation of postpartum blood loss within 24 hours following uncomplicated elective caesarean sections 2)Assessment of the requirement for other interventions like additional uterotonics/ haemostatic agents/ surgical methods for the management of the haemorrhage. 3)Evaluation of the need for blood transfusion & fall in postpartum haemoglobin levels during follow-up. 4) to evaluate & compare the adverse effects of carbetocin & oxytocin. Timepoint: Estimation of postpartum blood loss within 24 hours following uncomplicated elective caesarean sections	—

Measure

Time frame

Estimation of postpartum blood loss within 24 hours following uncomplicated elective caesarean sections 2)Assessment of the requirement for other interventions like additional uterotonics/ haemostatic agents/ surgical methods for the management of the haemorrhage. 3)Evaluation of the need for blood transfusion & fall in postpartum haemoglobin levels during follow-up. 4) to evaluate & compare the adverse effects of carbetocin & oxytocin. Timepoint: Estimation of postpartum blood loss within 24 hours following uncomplicated elective caesarean sections

—

Countries

India

Contacts

Public ContactDR NABNITA PATNAIK

AIIMS BIBINAGAR

drnabnitapatnaik@gmail.com8919995419

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026