Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: TRANSDERMAL KETOPROFEN PATCH: HALF OF THE PATIENTS WOULD BE SUBJECTED TO TRANSDERMAL KETOPROFEN PATCH 30 MG ONCE DAILY
Control Intervention1: TABLET KETOPROFEN: HALF OF THE POPULATION W
Sponsors
Debapriya Mahata
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients within the age group of 18-60 years and scheduled for day care oral surgeries. 2. ASA-I & II Patients. 3. Patients in the weight range of 50-80 kgs. 4. Patients who give consent for the study.
Exclusion criteria
Exclusion criteria: 1. History of allergy to the drug to be used in this study. 2. All pregnant and lactating females. 3. Duration of surgery less than 30 minutes or more than 2 hours from incision to closure. 4. Subjects with any associated history of bleeding disorder, allergy to NSAIDs, bronchial asthma, peptic ulcers, history of liver or kidney disease, abuse of drugs and alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the pain score postoperatively in day care oral surgery patients for seven consecutive days after patch placement and drug intervention by using Numerical pain rating scale at rest and during movement of jaws as in chewing which is dynamic painTimepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate and compare the number of rescue medications consumedTimepoint: 7 days;To evaluate and compare the episodes of adverse events of the drug including nausea, vomiting, gastrointestinal upset, constipation(difficult bowel movements) and application site reactionTimepoint: 7 days;To assess and compare quality of recovery postoperatively using QOR15 scaleTimepoint: 24 hours, 48 hours and 7 days post-operatively | — |
Countries
India
Contacts
Public ContactDebapriya Mahata
PGIMER, Chandigarh
Outcome results
None listed