Health Condition 1: N959- Unspecified menopausal and perimenopausal disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women undergoing oophorectomy (either unilateral or bilateral) for benign gynaecological conditions or for malignant conditions other than cancer ovary. 2. includes both Premenopausal women and Postmenopausal women.
Exclusion criteria
Exclusion criteria: 1.Women with known ovarian malignancies or other serious systemic diseases. 2.Women on long-term hormonal therapy (e.g., oral contraceptives, HRT) 3.Women with a history of pelvic radiation or chemotherapy 4.Malignant ovarian pathology on histopathology. 5. Women with prior ovarian surgeries that could alter fibrosis assessment. 6.Known genetic or autoimmune disorders affecting ovarian reserve.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the correlation between the degree of stromal fibrosis and ovarian reserve markers (AMH, FSH, AFC, stomal blood flow and ovarian volume) in perimenopausal women undergoing oophorectomy. Timepoint: within one week of planned surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate whether the degree of stromal fibrosis is associated with clinical characteristics (age, menstrual history) & surgical outcomes (complications, recovery time).Timepoint: Immediately post surgery | — |
Countries
India
Contacts
AIIMS, Bibinagar