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Comparing an Eye Injection and Eye Drops to Control Inflammation After Cataract Surgery

Posterior Subtenon Triamcinolone Acetonide and Topical Corticosteroids for Postoperative Inflammation Control Following Small Incision Cataract Surgery: A Randomized Controlled Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096620
Enrollment
66
Registered
2025-10-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H251- Age-related nuclear cataract

Interventions

Intervention1: POSTERIOR SUBTENON TRIAMCINOLONE ACETONIDE (40 MG/ML): Single injection of 0.5 mL (20 mg) triamcinolone acetonide administered in the posterior subtenon space at the end of small incisi

Sponsors

Sri Devaraj Urs Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 40 years Diagnosed with operable age-related cataract Undergoing uncomplicated SICS with posterior chamber IOL implantation

Exclusion criteria

Exclusion criteria: Pre-existing glaucoma or ocular hypertension History of uveitis or intraocular inflammation Complicated cataract like traumatic, subluxated, or mature cataract with phacolytic uveitis) Intraoperative complications like posterior capsular rupture, vitreous loss Systemic conditions affecting ocular inflammation like uncontrolled diabetes mellitus, autoimmune disorders Known allergy to corticosteroids Presence of corneal opacity or dystrophy affecting examination or IOP measurement

Design outcomes

Primary

MeasureTime frame
Degree of postoperative anterior chamber inflammation (cells and flare) on POD 1, 7, and 30Timepoint: Postoperative day 1, 7, and 30

Secondary

MeasureTime frame
Change in IOP from baseline Visual acuity improvement Incidence of adverse effects like steroid-induced IOP rise, subconjunctival hemorrhage Patient compliance & convenienceTimepoint: Postoperative day 1, 7, & 30

Countries

India

Contacts

Public ContactYeddula Venkata Rohith Reddy

Sri Devaraj Urs Medical College

yeddulavenkatarohithreddy@gmail.com9182662619

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026