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Study to Compare Bacterial Adhesion and Surface Changes on Zinc Oxide Nanocoated and Uncoated Orthodontic Wires in Patients

Comparative evaluation of surface morphology and Streptococcus mutans adhesion on retrieved Zinc Oxide nanoparticle coated stainless steel archwire vs uncoated wires- A randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096600
Enrollment
18
Registered
2025-10-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: Nanoparticle coated stainless steel wires: Zinc Oxide coating on 16x22 inch stainless steel wires used for orthodontic treatment Control Intervention1: Uncoated stainless steel wire: St

Sponsors

Dr Gunika Tayal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 12 to 30 years Patients requiring fixed orthodontic treatment with 0.022 MBT prescription Good general, gingival, and periodontal health

Exclusion criteria

Exclusion criteria: Systemic disorders Use of antibiotics or anti-inflammatory drugs in last 3 months Poor oral hygiene Known metal allergy Habit of pan masala or tobacco chewing, alcohol or aerated drink consumption

Design outcomes

Primary

MeasureTime frame
To evaluate streptococcus mutans adhesionTimepoint: after 4-6 weeks—

Secondary

MeasureTime frame
surface morphology (AFM analysis)Timepoint: after 4-6 weeks—

Countries

India

Contacts

Public ContactDr Gunika Tayal

Bharati Vidyapeeth(Deemed to be University) Dental College and Hospital Pune

veera.bhosale@bharatividyapeeth.edu7875571938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026