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A clinical study to compare the hemodynamic response to intubation(increase in Blood pressure and increase in heart rate) between C-MAC® video laryngoscope and C-MAC® video stylet(two types of intubation devices) in hypertensive patients scheduled for elective surgery under general anesthesia

Hemodynamic response to endotracheal intubation with C-MAC® video laryngoscope versus C-MAC® video stylet in patients with controlled hypertension scheduled for elective surgery under general anesthesia -A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096492
Enrollment
60
Registered
2025-10-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: I10- Essential (primary) hypertension Health Condition 3: I159- Secondary hypertension, unspecified

Interventions

Intervention1: Hemodynamic response (heart rate, blood pressure) to endotracheal intubation using the C-MAC® video laryngoscope in patients with controlled hypertension scheduled for elective surgery

Sponsors

Lady Hardinge Medical College and associated hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults belonging to the age group 18-60 years with controlled hypertension on antihypertensive therapy, without any other comorbidities (asthma/chronic obstructive pulmonary disease/diabetes mellitus/renal dysfunction/active liver disease)posted for Elective surgical procedures under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.Patients with Anticipated difficult airway(Mallampati classification III/IV),anatomical upper airway abnormality, cervical spine instability,restricted mouth opening, limited neck mobility 2 morbid obesity (BMI more than 30) 3.ischemic heart disease,cardiac arrythmias,significant heart disease 4. pregnant or lactating women 5. patients on beta blockers or clonidine

Design outcomes

Primary

MeasureTime frame
Mean (± SD) change in SBP (mmHg) and HR (bpm) in patients with endotracheal intubation via C-MAC® Video Laryngoscope and C-MAC® Video Stylet recorded at 1,3 and 5 minutes after endotracheal intubation from baseline (induction)Timepoint: Mean (± SD) change in SBP (mmHg) and HR (bpm) in patients with endotracheal intubation via C-MAC® Video Laryngoscope and C-MAC® Video Stylet recorded at 1,3 and 5 minutes after endotracheal intubation from baseline (induction)—

Secondary

MeasureTime frame
Median (interquartile range (IQR) POGO scoreTimepoint: Assessed at the time of intubation;Proportion of patients requiring OELM for achieving successful intubation.Timepoint: Assessed at the time of intubation;Mean (± SD) time taken in seconds for tracheal intubationTimepoint: Time from introduction of laryngoscope top the appearance of first square wave capnographic trace in first attempt;Proportion of patients in whom successful intubation could be achievedTimepoint: Assessed at the time of intubation;Proportion of patients identified with orodental trauma.Timepoint: Assessed at the time of intubation;Mean (± SD) difference in serum cortisol levels 2 minutes after intubation from the baseline levelsTimepoint: Assessed at the time of intubation & 2 minutes post intubation—

Countries

India

Contacts

Public ContactDr Rupali Swami

Lady Hardinge Medical College and associated hospitals

ranjusingh1503@gmail.com9811151285

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026