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Checking the eye nerve size before and after emergency brain surgery in head injury patients to understand brain pressures after head injury and how it changed during the course of surgery and its effects on recovery.

Comparison of Perioperative Changes in Optic Nerve Sheath Diameter and their Impact on Neurological Outcomes in Patients Undergoing Decompressive Craniectomy for Traumatic Brain Injury – A Prospective Observational Study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/10/096479
Enrollment
110
Registered
2025-10-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S062- Diffuse traumatic brain injury Health Condition 2: S065- Traumatic subdural hemorrhage

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

Jawaharlal Institute of Postgraduate Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged 18 to 65 years Isolated traumatic brain injury

Exclusion criteria

Exclusion criteria: Patients with orbital injury.Preoperative disorders such as neoplasms, inflammatory disorders of eye, graves disease, and extrinsic compression of optic nerve will be excluded. Patients undergoing bifrontal decompressive craniectomy. Polytrauma. Pregnant patients. Hemodynamic instability.Refusal to consent

Design outcomes

Primary

MeasureTime frame
To evaluate the degree of changes in optic nerve sheath diameter perioperatively in patients undergoing decompressive craniectomy for traumatic brain injury.Timepoint: Immediate preoperative,end operative, post operative 6hours, 12 hours, and 24 hours.—

Secondary

MeasureTime frame
To evaluate correlation between perioperative optic nerve sheath diameter and neurological outcomes of traumatic brain injury. To evaluate the perioperative change in optic nerve sheath diameter based on laterality of injury/side of Decompressive craniectomy. To evaluate the correlation between preoperative optic nerve sheath diameter(non invasive) and intraoperative invasive intracranial pressure ( icp)Timepoint: At postoperative 3 months—

Countries

India

Contacts

Public ContactDr Parismita Baruah

Jawaharlal Institute of Postgraduate Medical Education and Research

drprasannabidkar@gmail.com9442706168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026