Health Condition 1: R52- Pain, unspecified
Conditions
Interventions
Intervention1: Ketamine: Ketamine 0.5 mg per kg intravenous bolus administered 60 seconds before propofol injection for induction of anesthesia
Control Intervention1: Tramadol: Tramadol 1 mg per kg in
Sponsors
Pacific Medical College and Hospital Udaipur
Eligibility
Inclusion criteria
Inclusion criteria: a. Patients of either sex, aged between 18-60 years. b. Patients belonging to the American Society of Anesthesiologists Class I & II. c. Patients posted for elective surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: a. Patient not willing to give consent. b. Patients with a history of allergy or contraindication to either propofol, ketamine, or tramadol. c. Patients with anticipated difficult cannulation. d. difficulty in communication. e. patients with a history of epilepsy. f. Neurosurgical patients, with vascular disease and thrombophlebitis, infection on the dorsum of the hand. g. Renal and hepatic compromise. h. drug abusers, with chronic pain syndrome. I. pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the incidence and severity of pain on propofol injection following intravenous pretreatment with ketamine versus tramadol. Timepoint: To evaluate and compare the incidence and severity of pain during propofol injection following intravenous pretreatment with ketamine or tramadol, assessed at time intervals of 0, 1, 3, 5, 15, 30, 45, and 60 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the hemodynamic changes, such as heart rate and blood pressure, associated with each pretreatment drug during the induction of anesthesia. Timepoint: Baseline and after administration of the pretreatment drug | — |
Countries
India
Contacts
Public ContactDr Rama Kant
Pacific Medical College and Hospital
Outcome results
None listed