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Study to find out how levels of certain urine proteins differ in people with diabetes who have kidney disease and those who do not

Determination of Urinary Nephrin and Liver type Fatty Acid Binding Protein (L-FABP) levels in diabetic patients with and without nephropathy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/10/096442
Enrollment
106
Registered
2025-10-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E112- Type 2 diabetes mellitus with kidney complications

Interventions

Intervention1: Nil: Nil

Sponsors

Amritha Anil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Group A: Diabetic Group (Normoalbuminuria). Patients aged between 30 and 70 years old diagnosed with Type II diabetes mellitus. The urinary albumin to creatinine ratio of the patients should be less than 30 mg/g. Group B: Diabetic Nephropathy (Microalbuminuria). Patients aged between 30 and 70 years old diagnosed with Type II diabetes mellitus. The urinary albumin to creatinine ratio should be between 30–300 mg/g.

Exclusion criteria

Exclusion criteria: Patients who are not diagnosed with Type II Diabetes Mellitus are excluded

Design outcomes

Primary

MeasureTime frame
The study will help in assessing the role of nephrin and L-FABP as predictive biomarkers for Diabetic Nephropathy together, even before the appearance of traditional sign like albuminuria.Timepoint: 3 months- Quantitative analysis of parameters 6 months- Assessing the relationship between the parameters and the diabetic patients with and without nephropathy

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr B Shivananda Baliga

Kasturba Medical College, Manipal

shiva.baliga@manipal.edu9448770360

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026