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How Different Doses of Propofol Affect Blood Pressure After Induction in Elderly Patients

Association of propofol induction dose and post induction hypotension with varying doses of propofol in elderly in non cardiac surgery a randomised control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096412
Enrollment
168
Registered
2025-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems

Interventions

Intervention1: Induction of anesthesia with 1 mg/kg body weight of propofol: In patients undergoing general anaesthesia with endotracheal tube placement, induction will be done with 1 mg/kg body weigh

Sponsors

Manipal Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I/II/III PATIENT AGE MORE THAN OR EQUAL TO 65 YEARS OF ANY GENDER PATIENTS UNDERGOING GA WITH ET TUBE PLACEMENT

Exclusion criteria

Exclusion criteria: Patient refusal to participate in the study. Patient allergic to propofol. ASA IV grading of patients. Patients undergoing surgeries which do not need general anaesthesia or placement of endotracheal tube.

Design outcomes

Primary

MeasureTime frame
To evaluate the hemodynamic changes post induction in both doses of propofol by studying the vital signs in 2 groups for 11 mins post inductionTimepoint: To evaluate the hemodynamic changes post induction in both doses of propofol by studying the vital signs in 2 groups for 11 mins post induction

Secondary

MeasureTime frame
1 to asses induction quality score for 2 dses of propofol 2. to asses Ramsy Sedation scale at extubation 3.to asses adrele score prior to discharge from PACYTimepoint: Induction to 30 mins after extubation

Countries

India

Contacts

Public ContactDR HS MURTHY

Manipal Hospital,Old Airport Road

drhsmurthy@gmail.com9945469997

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026