An exploratory clinical study evaluating the efficacy of Panchwalkal Siddha Grita and Madnanand Modak in patients with Gudapaka (Ulcerative Proctitis) for improvement in clinical symptoms & sigmoidoscopic findings like mucosal healing

Efficacy of Panchwalkal Siddha Ghrita per-rectally and Madnanand Modak orally in Gudapaka (Ulcerative Proctitis): An Exploratory clinical study - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096406

Enrollment

Registered

2025-10-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K512- Ulcerative (chronic) proctitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients having ulcerative proctitis with mayo score 3-10. Patients having sigmoidoscopic evidence of ulcerative proctitis.

Exclusion criteria

Exclusion criteria: Patients having severe Ulcerative Proctitis with Mayo score more than 10 Presence of other colorectal pathologies like Fistula in ano, Hemorrhoids, Fissure-in-ano, Crohn’s disease,Colorectal Carcinoma, etc.Ulcerative Proctitis secondary to Tuberculosis, Herpes, etc. Presence of Uncontrolled Diabetes, Hypertension, Thyroid disorder.Pregnant and lactating females. Patients not willing to participate and not willing to give written informed consent.

Design outcomes

Primary

Measure	Time frame
Improvement in clinical signs and symptom score and Mayo Scoring i.e. improvement of score from baseline. Sigmoidoscopic improvement based of friability mucosal appearance, ulceration and bleeding.Timepoint: Baseline and 45th day and 75th day	—

Secondary

Measure	Time frame
Assessment of changes in inflammatory markers. (ESR, IL-6 CRP, Hb) Assessment of relapse rate, time required to relapse, sustained clinical remission rate. Assessment in quality of life score by using SF-36.Timepoint: Baseline and 45th day and 75th day	—

Countries

India

Contacts

Public ContactDrYogesh Badwe

All india institute of Ayurveda

drvyasayu@gmail.com7838957972

Outcome results