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How Blood Lactate Levels Reflect Oxygen, hemoglobin and Acidity Changes in Critically Ill Patients

CORRELATION OF SERUM LACTATES WITH PH, HB AND PAO2 IN PATIENT ADMITTED IN CRITICALCARE UNIT. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/10/096370
Enrollment
80
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R799- Abnormal finding of blood chemistry, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: NIL: NIL Intervention3: Nil: Nil

Sponsors

Dr Akshaya N Shetti
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients admitted to ICU requiring ABG analysis. Age more than 18 years. Informed consent from patient/attendant.

Exclusion criteria

Exclusion criteria: Chronic liver failure (affects lactate clearance). Known inborn errors of metabolism. Patients on metformin toxicity / cyanide poisoning.

Design outcomes

Primary

MeasureTime frame
Negative correlation between lactate & pH, HCO3. Negative correlation between lactate & Hb. Negative correlation between lactate & PaO2 Positive correlation between lactate & PaCO2 (in uncompensated states). Higher lactate associated with increased ICU mortality.Timepoint: Baseline—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr. Akshaya N. Shetti

Pravara Institute Of Medical Sciences, Loni

aksnsdr@gmail.com7507807673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026