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Comparison of pain relief in patients with low back ache, who have undergone biacuplasty with intradiscal steroid vs biacuplasty with intradiscal platelet rich plasma

Comparison of intradiscal platelet rich plasma vs steroid in patients undergoing biacuplasty for discogenic low back pain. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096366
Enrollment
28
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M513- Other thoracic, thoracolumbar andlumbosacral intervertebral disc degeneration

Interventions

Intervention1: Intradiscal platelet rich plasma injection: After the patients undergo biacuplasty, they will be immediately injected with 2ml of PRP-LP (Leucocyte poor PRP) prepared in Precurecell LP

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults aged between 18–65 years Patients with chronic low back pain for more than 3 months MRI evidence showing disc degeneration or annular tear Patients with failed conservative therapy of at least 3 months.

Exclusion criteria

Exclusion criteria: Patients with radiculopathy or spinal canal stenosis Patients who have undergone prior lumbar surgery Patients with spinal infection, tumors, fractures, or instability Currently on anti-coagulants or patients with coagulopathy Pregnant or lactating women Patients with known allergy to drugs and materials used .

Design outcomes

Primary

MeasureTime frame
To compare the analgesic efficacy of biaculoplasty + intradiscal leucocyte poor PRP and biaculoplasty + intradiscal steroid in patients with chronic discogenic low back pain at 3,6 and 12 months after the procedure using NRS (Numerical rating scale) Timepoint: To compare the analgesic efficacy of biaculoplasty + intradiscal leucocyte poor PRP and biaculoplasty + intradiscal steroid in patients with chronic discogenic low back pain at 3,6 and 12 months after the procedure using NRS (Numerical rating scale)—

Secondary

MeasureTime frame
Compare functional improvement using the Oswestry Disability Index (ODI) in patients with chronic discogenic low back pain after biaculoplasty + intradiscal leucocyte poor PRP and biaculoplasty + intradiscal steroid at 3,6 and 12 months after the procedure. Evaluate quality of life changes using SF12 at 3,6 and 12months Assess patient satisfaction using Patient Global Impression of Change (PGIC) scale To identify predictors of treatment success in each group. Monitor adverse events. Timepoint: 3, 6, 12 months—

Countries

India

Contacts

Public ContactAnuj Jain

All India Institute Of Medical Sciences, Bhopal

anuj.anesth@aiimsbhopal.edu.in9755702644

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026