A study to see if gentle electrical stimulation machine on the head and daily time-based exercises can help reduce tiredness, anxiety, and depression in women with breast cancer who are getting chemotherapy.

Transcranial Direct Current Stimulation(tDCS) and Circadian Rhythm Time-Based Conventional Exercises for Fatigue, Anxiety and Depression in Breast Cancer patients undergoing chemotherapy:A Single-Blind Randomized Controlled Trial. - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096360

Enrollment

Registered

2025-10-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: tDCS with circadian rhythm time-based exercises: Participants will receive active tDCS over the dorsolateral prefrontal cortex (DLPFC) at 2 mA for 20 minutes per session, 5 sessions per

the current will be ramped up for 30 seconds and then turned off to mimic sensations of stimulation.The exercise program combines daily aerobic walking and resistance band training to reduce fatigue a

Eligibility

Inclusion criteria

Inclusion criteria: diagnosed with stage I–III breast cancer, scheduled to receive adjuvant or neoadjuvant chemotherapy, received approval from a medical oncologist to participate in the trial

Exclusion criteria

Exclusion criteria: traumatic brain injury or concussion with residual symptoms, mobility issues that require a mobility aid or an injury/illness that would prohibit exercising, self-reported physical or cognitive condition that prevented women from participating independently

Design outcomes

Primary

Measure	Time frame
FACIT-Fatigue scale Timepoint: total 4 weeks of protocol,outcome will be assessed at baseline and after 4 weeks	—

Secondary

Measure	Time frame
Beck Anxiety Inventory Timepoint: which will be assessed at baseline and after 4 weeks;Beck Depression InventoryTimepoint: which will be assessed at baseline and after 4 weeks	—

Countries

India

Contacts

Public ContactDr Sanjiv Kumar

KAHER Institute of Physiotherapy

sanjiv3303@rediffmail.com9448745648

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026