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Comparison of preoperative nebulisation with Magnesium Sulphate and ketamine for prevention of postoperative Sore Throat After Endotracheal Intubation in a Tertiary care Centre

Comparison of preoperative nebulisation with Magnesium Sulphate and ketamine for prevention of postoperative Sore Throat After Endotracheal Intubation in a Tertiary care Centre - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096357
Enrollment
120
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine nebulisation: Ketamine nebulisation with 50 mg preoperative Control Intervention1: Magnesium Sulphate: Magnesium Sulphate nebulisation 500 mg preoperatively

Sponsors

Sapthagiri Institute Of Medical Sciences And Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA 1 and 2 2.General anaesthesia requiring Endotracheal intubation 3.Informed consent

Exclusion criteria

Exclusion criteria: Existing sore throat Hypersensitivy to study drug Oral surgeries BMI greater than 30 Pregnant and lactating women Patients with upper respiratory tract symptoms

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of ketamine nebulisation and magnesium sulphate nebulisation to decrease incidence of postoperative sore throat in patients undergoing endotracheal intubationTimepoint: Baseline,2hrs,4 hrs,6 hrs,12 hrs,24 hrs—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactPrashanth Prabhu J

Sapthagiri Institute Of Medical Sciences And Research Centre

prashanthjnpl@gmail.com9035067161

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026