Health Condition 1: J988- Other specified respiratory disorders
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
JERUSHA MATHEWS
Eligibility
Inclusion criteria
Inclusion criteria: Patients more than 18 years on invasive mechanical ventilation admitted in Kasturba hospital Patients in ARFA (i.e., not entirely fulfilling the diagnostic criteria of ARDS) Presence of any of the following radiological features(C-X-ray, Lung ultrasound,CT) 1.Alveolar infiltrates (can be hemorrhagic) 2.Interstitial infiltrates 3. Atelectasis 4.Consolidation 5.Ground glass opacities 6.Air bronchogram in lung ultrasound Respiratory Symptoms (at least one) New or increased cough New or increased sputum production Dyspnea Pleuritic chest pain Other Signs or Findings (at least one) Abnormal lung sounds (rhonchi or rales) Fever (more than or equal to 100.4 °F) Leukocytosis or unexplained bandemia (above normal limits for laboratory) Hypoxia (less than 90%)
Exclusion criteria
Exclusion criteria: 1)ARFA patients on NIV 2)Patients not recruited within first 24 hours of IMV 3)Patients already having pre-existing Pulmonary Artery Hypertension 4)Patients having pre-existing EF of less than 40 per cent 5)Patients on any biological agent, prednisone equivalent of more than 10 mg per day and 700 mg cumulative dose , antiproliferative agents and B or T cell depletion medications 6)Patients having malignancies
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: nil | — |
Primary
| Measure | Time frame |
|---|---|
| Demographic , biochemical and Echo/USG data will be collected within 72 hours of admission which is part of standard of care. Hence the investigator will only collect the reports. Outcome will assessed based on duration of Icu stay, use of vasopressors and mechanical ventilation. Outcomes will be analyzed at the time of discharge – Improved/ExpiredTimepoint: 24 HOURS , 72 HOURS | — |
Countries
India
Contacts
Public ContactVASUDEVA ACHARYA
KASTURBA MEDICAL COLLEGE , MANIPAL
Outcome results
None listed