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Effect of special coated orthodontic wires on smoothness and reduction of cavity causing bacteria in the mouth

Evaluation of the effect of Titanium Dioxide-coated stainless steel archwires on surface roughness and adhesion of Streptococcus mutans: A Randomized Clinical Trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096339
Enrollment
34
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K14- Diseases of oral cavity and salivary glands

Interventions

Intervention1: Titanium dioxide nanoparticle-coated stainless steel archwire: Titanium dioxide nanoparticle-coated stainless steel archwire (0.016” × 0.022”) inserted for 3 weeks. Control Intervention

Sponsors

Dr Sajal Khare
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 12–30 years Undergoing fixed orthodontic therapy with 0.022” × 0.028” MBT prescription brackets Good general, gingival, and periodontal health No history of allergy to materials used

Exclusion criteria

Exclusion criteria: Systemic disorders Antibiotic or anti-inflammatory use within last 3 months Poor oral hygiene Motor disabilities Smokers alcohol or aerated drink consumers Craniofacial deformities

Design outcomes

Primary

MeasureTime frame
Colony count of Streptococcus mutans on retrieved archwiresTimepoint: after 3 weeks—

Secondary

MeasureTime frame
Surface roughness comparison of coated vs. uncoated archwires using Atomic Force Microscopy (before and after intraoral use). % reduction in bacterial adhesion between groups.Timepoint: after 3 weeks—

Countries

India

Contacts

Public ContactDr Sajal Khare

Bharati Vidyapeeth (Deemed to be) University Dental College & Hospital, Pune

veera.bhosale@bharatividyapeeth.edu7875571938

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026