Health Condition 1: Z00-Z99- Factors influencing health status and contact with health services Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: oral pregabalin: Group P patients will receive oral pregabalin 150 mg 1 hour prior to surgery.Patients will be preoxygenatated and standard anaesthesia protocol will be followed after t
Sponsors
SHUBHADA BHAGAT
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1 scheduled for elective surgery under general anaesthesia requiring orotracheal intubation
Exclusion criteria
Exclusion criteria: Following patients will be excluded from the study 1 Refusal to consent 2 Anticipated difficult airway 3 Patients whose intubation procedure will last more than 15 seconds. 4 Patients with known allergy to study drugs 5 Patients requiring more than 1 intubation attempt 6 Neurosurgery patients 7 Cervical spine instability 8 Patients having history of cardiac or liver disease 9 Patients having baseline heart rate less than 50 in min or having AV blocks 10 Morbid obesity 11 Pregnant and lactating females
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine whether a statistically significant reduction in hemodynamic response to laryngoscopy and intubation occurs with 150 mg oral pregabalin as compared to 1 mcg/kg of iv dexmedetomidine.Timepoint: HR, SBP, MAP, DBP at 1 min, 3 min, 5 min and 10 min post intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects like bradycardia, hypotension in intraoperative and postoperative period. Sedation, nausea, vomiting will be noted in postoperative period. Timepoint: Intraoperative and postoperative period for 2 hours | — |
Countries
India
Contacts
Public ContactSHUBHADA BHAGAT
PGIMS, ROHTAK, HARYANA
Outcome results
None listed