Health Condition 1: F200- Paranoid schizophrenia
Conditions
Interventions
Intervention1: High-definition transcranial direct current stimulation (HD- tDCS): 20 sessions (2 sessions per day, 45 minutes apart, 5 days/week for 2 weeks), administered in a controlled clinical se
Sponsors
Sri Guru Ram Rai Institute of Medical and Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Provided written informed consent. 2. Diagnosis of schizophrenia as per (DSM-5 criteria). 3. Age: 18 50 years. 4. Patient should be stable on same antipsychotic medication. 5. Hindi MOCA score of less than 26.
Exclusion criteria
Exclusion criteria: 1.History of seizures or neurological disorders. 2. Patients with implanted metallic devices 3. Substance dependence (except nicotine or caffeine) in the past 6 months. 4. Any other major mental disorders. 5. Patient is uncooperative for the procedure. 6. Patients with neurological disorders with history of epilepsy, organic brain damage or any neurological procedures 7. Patients with significant unstable medical conditions like uncontrolled hypertension, complicated diabetes mellitus, organic failures, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Hindi MoCA and SCoRS scores across T0, T1, and T2 Analysis Mixed effects repeated measures ANOVA with group active versus sham as the between subjects factor and time T0 T1 and T2 as the within subjects factor conducted separately for Hindi MoCA and SCoRS scoresTimepoint: baseline,7 days,15 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in PANSS, WHO-QOL, & CGI-S scores. Timepoint: baseline, 7 days, 15 days | — |
Countries
India
Contacts
Public ContactDr Dhruv Khanna
Sri Guru Ram Rai Institute Of Medical and Health Sciences
Outcome results
None listed